Actin-Like 6B antibody (AA 1-280)

Catalog No. ABIN6136481

The Rabbit Polyclonal anti-Actin-Like 6B antibody has been validated for WB, IHC and IF. It is suitable to detect Actin-Like 6B in samples from Human.

Quick Overview for Actin-Like 6B antibody (AA 1-280) (ABIN6136481)

Target: Actin-Like 6B (ACTL6B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Actin-Like 6B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Actin-Like 6B Antibody

Binding Specificity: AA 1-280

Sequence: MSGGVYGGDE VGALVFDIGS FSVRAGYAGE DCPKADFPTT VGLLAAEEGG GLELEGDKEK KGKIFHIDTN ALHVPRDGAE VMSPLKNGMI EDWECFRAIL DHTYSKHVKS EPNLHPVLMS EAPWNTRAKR EKLTELMFEQ YNIPAFFLCK TAVLTAFANG RSTGLVLDSG ATHTTAIPVH DGYVLQQGIV KSPLAGDFIS MQCRELFQEM AIDIIPPYMI AAKEPVREGA PPNWKKKEKL PQVSKSWHNY MCNEVIQDFQ ASVLQVSDSP YDEQVAAQMP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ACTL6B (NP_057272.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Actin-Like 6B

Target: Actin-Like 6B (ACTL6B)

Alternative Name: ACTL6B

Background: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.,ACTL6B,ACTL6,BAF53B,arpNalpha,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Neural Stem Cell marker,ACTL6B

Molecular Weight: 46 kDa

Gene ID: 51412

UniProt: O94805